Serious Sam 2
The following weapons can be seen in the game Serious Sam 2:
Dual Colt Anacondas are one of the starting weapons of Sam "Serious" Stone in the game. Have unlimited ammo, but must be reloaded after every 12 shots. Fires continuously if the fire button is held. It must be also noted that the in-game model of the revolver lacks the extractor rod and has a different cylinder latch.
IMI Mini Uzi
Dual Mini Uzis are one of the few non-fictional usable weapons in the game, replacing the Thompson Submachine Gun from the previous two games. The Mini Uzis feature an unusable (but good-looking) radar-like display on the top, which obstructs the charging handle and sights. The game refers to the weapon as "Dual Uzis". The ammo cap is 1,000 bullets for this weapon. Reloading is not necessary.
At one point Sam states that the "Uzi" fires 480 rounds per minute. That is incorrect, because the Mini Uzi has a cycling rate of 950 round/minute, which is nearly double of what Sam said.
IMI Micro Uzi
Sam can be seen on a photo with dual Micro Uzis.
Handheld M134 "Minigun"
Cyborg soldier enemies are seen using Miniguns in the game. A 9-barreled version is usable by Serious Sam. The Minigun shares ammo with the dual Mini Uzis. The cycling rate is surprisingly low, but the damage per bullet is high. About 200-250 low-level enemies can be killed with a fully loaded (1000 rounds) Minigun before it runs empty, making it the ultimate weapon along with the Plasma Rifle. This is one of the rarest weapons in the game.
The "Sniper Rifle" is a somewhat altered Heckler & Koch HK91 civilian rifle with a shorter handguard, futuristic variable-zoom scope with built-in rangefinder, and a flash suppressor. Most enemies will die from one well-placed shot. Hilariously, it deals about three times more damage if Sam uses the scope when shooting. It is modeled with a 20-round magazine, but in fact it holds 50 rounds and doesn't need to be reloaded.
The "Machine Gun Turret" is seemingly based on the Maxim 1895, the barrels rotate like a chaingun when firing and the ammo cans say "110 mm Vulcan Turret"
Mk 2 Hand Grenade
Mk 2 hand grenades appear as usable equipment with high damage and splash radius. The grenades explode on contact. Sam can carry a total of 30 grenades.